|
| |
 | Chemical Structure |
|
 |
| Chemical Formula |
|
C46H80N2O13 |
| Molecular Weight: |
|
869.15 |
| Cas No.: |
|
108050-54-0 |
| Chemical Name |
|
Tilmicosin (IUPAC name): (10E,
12E)-(3R,4S,5S,6R,8R,14R,15R)-14-(6-deoxy-2,3-di-O-methyl-b-d-allo-hexopyranosyoxymethyl)-5-(3,6-dideoxy-3-dimethylamino-b-d-gluco-hexapyranosyloxy)-6-[2-(cis-3,5-dimethyl-piperidino)ethyl]-3-hydroxy-4,8,12-trimethyl-9-oxoheptadeca-10,12-dien-15-olide
Chemical Abstracts Services Name: tylosin,
4A-O-de(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-20-deoxy-20-(3,5-dimethyl-1-piperidinyl)-(20(cis:
trans)) |
| Synonyms |
|
20-Deoxy-20-(3,5-dimethylpiperidin-1-yl)-desmycosin,
Tilmicosin Phosphate |
| Compliance |
|
USP24 |
|
| Description |
|
A
white or off-white powder, Freely soluble (1500 mg/L or greater) in organic
solvents (hexane, acetone, acetonitrile, chloroform, dichloromethane, ethyl
acetate, methanol, tetrahydrofuran); water solubility is temperature and pH
dependent, but is 566 mg/mL at pH 7 and 25°C.
|
| Indications |
|
Tilmicosin is a macrolide antibiotic developed
for veterinary use. It is recommended for treatment and prevention of
pneumonia in cattle, sheep and pigs, associated with Pasteurella haemolytica,
P. multocida, Actinobacillus pleuropneumoniae, mycoplasma species and other
microorganisms found sensitive to this compound. It is an antibiotic medicine with great antibiotic
effect and broad antibiotic spectrum . Not show resistance and
cross-resistance with other antibiotic often used in clinic. Mainly used in
the Pleuropneumonia and the infection caused by Pasteurellaceae ,
Pasteurella and mycoplasma |
| Specification |
|
Tilmicosin consists of 82-88% cis isomer and
12-18% trans isomer, as determined by liquid chromatographic
assay.(Assay:Min. 85%) |
| Dosage & Administration |
|
formulations of tilmicosin include an injectable
for use in cattle and sheep (30% Injection) and premix formulations for
swine (4%, 10% & 20% Premix). The recommended dose of the injectable
formulation in both cattle and sheep is a single subcutaneous (SC) injection
of 10 mg/kg BW. Recommended dose for swine in feed is 200-400 mg/kg of feed
for 10 to 21 days, equivalent to 8-20 mg/kg BW per day. |
| Packing: |
|
1 Kg or 5 Kgs in one Aluminum Tin; 10 Kgs per
carton. |
| Storage |
|
Protected from light , stored hermetically and in
a dry place. |
| Shelf Life |
|
2 years. |
| Remarks |
|
In need of further
information, please kindly us at:
biok@vetamo.com or
davidvan2000@homtail.com or call our direct phone: 0086 133 5582 2008 |
|
